Studying the Cell of the Homo Sapien, and Genomic Stability, DDR

Studying the Cell of the Homo Sapien, and Genomic Stability, DDR

Genomic Stability is essential for all living organisms and is safeguarded by DNA damage response systems and pathways.

“DDR or DNA Damage Response” Pathways and Exit Cycles for Cells

These biological mechanisms protect cells against intrinsic insults and from assaults from the environment, such as “Reactive Oxygen” weakening the oxygen bonds, and “Nitrogen Species. ” Are we being protected in DNA? Are our Genomes Stable?

DNA or insults from the environmental assaults cause single strand breaks, and double strand breaks in our Helix, during transcription. Adding stress from the environment is going to cause damage to DNA. Proteins like Spike proteins, or effective proteins misfolding give ineffective protection to our DNA.

The DNA Damage Response from those proteins,  will exit cells from the cell cycle regulated apoptic pathways, and eliminate them by programmed cell DEATH, leaving the DNA irreparable. The Genome Integrity is then not Safeguarded.

How do fungicides, pesticides, herbicides, and anhydrous-ammonia for nitrates, work in the DNA Damage response pathways?

How does Hormone Replacement  Therapies, estrogen, progesterone,  work when pumped full of synthetic chemistry compounds. It is known that cancers are the instability of cells. Breast cancers were on the increase from Hormone Replacement Therapies. What other damage was being caused when cells exit via the DNA Damage Response pathways? The DNA becomes irreparable.

Aids Cocktails of Synthetic Chemistry Compounds….All those compounds of chemistry pumping through our DNA systems, and did we expect there to be no damage to the DNA via the Damage Response pathways and cycles.

Pumping Homo Sapiens full of Synthetic Chemical Compounds for breast increases, breast reductions, penis removal, penis increases, hormone treatments, Botox injections, lip increases, eye crease removal, all being done with Synthetic Chemistry Compounds. What about the DNA Damage Response Systems and Pathways and Exit Cycles? Did you expect the DNA to be reparable?

Regions of DNA where intense transcriptions takes place there is loss of Chromatin Structures and undergo large scale changes which make more “Genomic Vulnerability.”

A 12 letter bases spliced in sequence with a human enzyme into a biological attack on our biology, hosted by humans, spread via airborne 27 feet by humans homo sapiens, the concept of organic chemistry comes to mind and when combined leads to more Genome Instability. Covid 19. Human Extinction comes to mind as I write this. Assaults from Reactive Oxygen. Respiratory problems, blood diseases, attacks on the cells in the White and Grey Matter in the brain in the Frontal Temporal Cortex leading to Aphasia, and the Supplementary Motor Cortex, Area 4, that leads to Muscle Diseases, Myocardial infarction, Pericardial, lung diseases and dead cells found in the lining, on the autopsies in 2020 via Dr. Hansen. Are these DNA every going to be reparable?

No One expected how much we were going to learn from studying these cells. Atom bombs, Agent Orange, Nuclear leaks, Emissions from cars and fuels. Are our cells and DNA every going to be reparable now?

Carolyn d Hogarth Canada

 

 

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