Proteins Mis-folding cause degenerative disease and Covid 19 caused mis-folding Proteins and the proof is in the research that has been proven up to and including April 2023.

A protein misfolds when it follows the wrong pathway in a in folding pathology, or in the energy, causing mis-folding which does occur. A protein mis-folding is a common cellular event that can occur through the lifetime of a cell  and this is caused by different events including genetic mutations, translational errors. abnormal protein buildup, protein modification, thermal or oxidation stress and incomplete information on mRNA.

Dominant negative mutations are a third way by which proteins mis-folding can cause disease and this is through a Dominant mechanism which occurs when a mutant protein antagonizes the function of the wild type protein activity even in hetero-zygotes. Oxygen shortage can also cause proteins to mis-fold.

The “Prion” protein in Creutzfeldt – Jakob disease also known as mad cow disease is an example of a misfolding protein gone rogue. This protein is not only irreversibly misfolded but it converts functional proteins into a twisted state. Something like some forms of dementia in a homo sapien.

One way a eukaryotic cell  handle the complication of misfolded proteins is by destroying them through “ubiquitin proteasome,” system. To do this eukaryotic possesses specialized ubiguitin protein ligases, that have the capacity to recognize misfolded proteins normally folded proteins. 

Genetic mutations that cause misfolding of proteins is a primary cause of Alzheimer disease, differing forms of dementia. Parkinson’s, Huntington’s, Cruetzfeldts- Jakob disease, cystic fibrosis, Gaucher’s disease and many others are caused by misfolding proteins. Many degenerative disorders where the Frontal Temporal Areas and Area 4 are involved and the brain stem, limbic systems, and all sense systems can occur. There are types of Diabetes like Melletis type 2, from the amyloid beta that are caused by misfolding proteins. That one noted in research by Dr. Campbell in Covid 19. A protein misfolding disease due to accumulation of the amyloid beta causes problems in the psychopathology, neuron-pathology, and biochemical pathways, and characteristics of the potentiality of these mechanisms causing death to a victim, is a highly probable outcome.

Covid 19  acute brain abnormalities are suggesting etiology were present in the Frontal Temporal Area, area 4, Frontal lobe network, and showed changes in the patients brains  after covid 19 infection. fMRI’s revealed significant brain abnormalities from Covid 19 in autopsies. Covid 19 caused immune-suppression, and in brain cells weakening our immune system, which usually respond to a significant decrease in microgila  cells that serve as the First line of defence for the “Central Nervous System” and in the Amygdala and the limbic system, and in the Cerebellum brain.

People who had Covid 19 are at an elevated risk of developing neurological conditions within a few years of the infection. Covid does cause negative impacts on the body composition and muscle function and quality of life. There are multiorgan effects of autoimmune disease,  and serious body inefficient conditions in many body systems including the heart, kidneys, lungs, liver, womb, bowels, throat, nose, eyes, skin, neurologically affected by Covid 19.

Along with many cortices, the Executive Function brain area is inclusive, the Superior Temporal Sulcus, the Intraparietal Sulcus, and the Pre-motor Cortex also included. These are areas where comparisons are activated, and combining all information gathered for a fully comprehensive study of Past and Present Comparisons. There are serious consequences to Covid 19 and intelligence in our future. Number Values in abstract forms can be effected in the Temporal Sulcus when cells are destabilized from Proteins misfolding.

This is to explain the consequences of the Wuhan Studies and Researched man manipulated sequentia of Gain of Function Research.

Written by Carolyn d Hogarth from Canada.