Are we mind, genes, appearances on the outside, clothing, big butts, big boobs, or something else? You might not be who you think you are.

Is the human species at the end of an Evolutionary line, or will we be evolving into something else? Something entirely different?  I can suggest with an open mind, we are indeed evolving into something else if we feed our genes, Aids’ Cocktails with synthetic chemistry compounds, or steroids, a synthetic chemical compound that can change your DNA and your next generations. It can change a physique, temperament, and personality completely.  Along with Hormonal Replacement therapies, as found out do change DNA, personalities, pathologies, and indeed are synthetic chemistry compounds of complete danger to the human genome.  HRT changed the human genome and caused cancers, and progesterone caused depression, and put stress on the DNA, and some HRTherapies caused mood swings suggesting the amygdala system along with the limbic systems and pathways effected, and estrogen causing cancer growths to be larger suggests a huge change in the human genome. Steroids, hormones induced expression of genes, and a large scale alteration of the genome architecture, and added major stress at the DNA level. Transcription active regions are generally unstable and prone to breakage due to torsional stress and local depletion of nucleosomes that make DNA more acessable to damaging agents such as the region of DNA damage Response for repair, the ( DDR system). The DNA damage response system is a complex DNA sensor  protein that detects poly (ADP- ribose for example) polymerase , the ataxia – telangiectasia, when mutated ATM kinase and cannot be a central regulator.

Genomic Stability is essential for all living organisms and is safeguarded by different complex and coordinated DNA Damage Response pathways. These mechanisms protect cells against intrinsic insults or assaults such as “Reactive Oxygen” and “Nitrogen Species.” DNA and insults or assaults from environments cause single strand breaks, or sometimes Double strand breaks in our helix during transcriptions. Further some proteins like Spike proteins misfolding, or effective proteins, give ineffective protections.

The DNA damage response, DDR, from proteins, will exit cells from the cell cycle regulated apoptic pathways and eliminate them by programmed cell death, and then the DNA cannot be repaired . The GENOME INTEGRITY is then not safeguarded.

If you look at cancers on the rise from Covid 19 for example, from synthetic chemistry compounds, cancer cells are characterized by cell instability. The concept of synthetic chemistry compounds  when combined can cause “synthetic lethability.”

Regions of our DNA where intense transcriptions take place lose a chromatin structure and undergo large scale changes which makes the genome more vulnerable to DNA Damage Response systems, hence killing of cells.

In Covid 19, the 12 letter base sequence plus a homo sapien enzyme – which has to have had an intense transcription area on the human genome, left our genome open to the DDR. Treatments to inhibit these damaged pathways of DNA expression and associated genes and pathways reduce recombining of genomes and the cells are then killed off by the DDR.  It illicits changes in the transcription area (mRNA) and targets gene transcription areas and modulating structures. There are serious adverse affects from synthetic chemistry compounds that have shown to be presenting in differing disease forms,  and the killing of cells in the Frontal Temporal Cortex and the Supplementary Motor Cortex area of the brain, and associated pathways, causing a serious group of Aphasia and Muscle Diseases, along with many other forms of presenting diseases.

In knowing how the human brain interacts with synthetic chemistry compounds  from our environment shows the importance of our biosphere for biological organisms, on our home planet. This is the biosphere we depend on for adaptation and survival of the Optimum brain mechanics. Our health of the biological organisms, called homo sapiens, leads the Optimal brain with a functioning genome to self direct, self actualize, self adapt, self survive, in our diverse atmosphere and biosphere, for All forms of organisms.

In the absence of Scientific tools,  we then do not have the capacity to contemplate these questions that define who we are as humans. Our capacity to formulate answers for survival need understanding for modifying our behaviour in adaptation in our biosphere.

Scientific Revolutions have tools that will make enormous changes for our children.  Deciphering manipulation of the molecules of DNA and operating systems, of the homo sapien, define species typical and individual attributes of every organism on earth.

Meaning of Life changes with biological tools and informed understanding of the human genome of All MPLGBTQAI. the Alphabet family of homo sapiens. We will learn to read all 3 billion base pairs and the DNA differences that make our individual uniqueness. We will learn the genetic basis for disease and those that affect the mind. Knowing potentiality, of biomedical Science and the impact this will have on our own future of the homo sapien,  gives me a great deal of hope for the future.

Brown, black, white or multicoloured cells are indeed there for skin to cover our frame that carries the inner workings of a beautiful homo sapien miracle of Mother Earth. To be Racist at this point is to defeat every biological tool learned about, over the last 200 years. To be killing because of skin colour, or fear, is to defeat man kind and its progress.

Carolyn d Hogarth

The Optimum brain and biological tools that we have accumulated over 200 years for our Children’s health, are a goal for education. Make sure and check with your doctors, before taking any action on anything from Science. The biomedical group should have more answers for you. CDH